在非医院心脏骤停和复苏后 (TEMP-CARE) 使用或不使用温度控制装置控制发烧:一项随机临床试验的研究方案
Johan Holgersson1,2, V Niemelä3, M B Skrifvars3
1Department of Clinical Sciences Lund, Anesthesia and Intensive Care, Lund University, Lund, Sweden.
Acta anaesthesiologica Scandinavica
|April 13, 2025
概括
使用反控制装置进行心脏骤停后的发烧管理可能会改善患者的治疗结果. 这项试验调查了它对心脏骤停幸存者的死亡率和功能状态的影响.
科学领域:
- 关键护理医学 关键护理医学
- 神经学 神经学
- 心脏病学 心脏病学
背景情况:
- 发烧是心脏骤停后的一个已知的并发症,与增加的脑损伤有关.
- 使用反控制设备进行主动发烧管理,以改善心脏骤停后以患者为中心的治疗结果的有效性仍然不确定.
研究的目的:
- 为了研究带有或没有反控制温度控制装置的发烧管理对患者在医院外心脏骤停后的结果的影响.
- 评估温度控制策略对死亡率,功能状态和不良事件的影响.
主要方法:
- 该TEMP-CARE试验是一个随机的国际多中心优势试验,评估温度管理作为更大的STEPCARE试验的一部分.
- 患者随机分配到带有或没有反控制装置的发烧管理,如果发烧 (≥37.8°C) 发生在72小时内,则准≤37.5°C.
- 主要结局是六个月的全因死亡率;次要结局包括功能结局和密集护理相关的不良事件.
主要成果:
- 这个部分不适用,因为摘要不包含结果. 这是一个协议描述.
结论:
- 该TEMP-CARE试验将确定使用反控制装置积极控制发烧是否可以改善心脏骤停后患者重要的结果.
- 研究结果将为临床实践提供有关心脏骤停后护理中最佳温度管理策略的信息.
更多相关视频
06:59A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
30.3K
06:25Cooling or Warming the Esophagus to Reduce Esophageal Injury During Left Atrial Ablation in the Treatment of Atrial Fibrillation
Published on: March 15, 2020
9.3K
相关概念视频
Methods of reducing fever
616
The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Pharmacological Methods of Reducing Fever:
616
Increased Body Temperature
619
A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
619
Decreased Body Temperature
580
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
580
Increased pulse rate
624
Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
624
Types of Fever
308
Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Here are the different types of fever:
308
Factors Affecting Body Temperature
3.6K
As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may include:
Factors may include:
3.6K
