术后疼痛和内牙治疗后的围牙治疗使用帕奇米酸修饰的环氧树脂根管密封剂:双盲随机对照试验
Shiza Yezdani1, Monisha Khatri1, Sampath Vidhya1
1Department of Conservative Dentistry and Endodontics, SRM Dental College, Ramapuram, Chennai, Tamil Nadu, India.
Journal of endodontics
|April 13, 2025
概括
添加帕奇米酸 (PAC) 到AH Plus密封剂减少了手术后的立即疼痛,并在内牙治疗中改善了周周 (PA) 病变的愈合. 这种增强的密封剂证明了在有死肉质的牙中对PA愈合的显著长期益处.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 牙科材料科学 牙科材料科学
- 恢复性牙科 恢复性牙科
背景情况:
- 牙周炎和死肉肉需要有效的根管密封剂.
- AH Plus (AHP) 是一种常见的环氧树脂密封剂,但它对术后疼痛和愈合的影响需要优化.
- 帕奇米酸 (PAC) 正在因其潜在的抗炎和治疗特性而在内牙科应用中受到研究.
研究的目的:
- 为了评估添加帕奇米酸 (PAC) 加入环氧树脂根管密封剂 (AH Plus) 对术后疼痛的影响.
- 评估PAC修改的AH Plus对牙内 (PA) 病变愈合的影响,这些病变发生在牙内和牙顶牙周炎的牙中.
主要方法:
- 50颗患有死性肉质和性牙周炎的牙接受了内治疗,并被分为两个组:AH Plus (AHP) 和AHP修改了PAC (AHP/PAC).
- 术后疼痛的评估是在基线,24小时和7天使用视觉模拟尺度进行的.
- 周周 (PA) 病变的大小,体积和PA体积指数使用数字放射学和形光束计算断层扫描 (CBCT) 在各种随访间隔评估,长达12个月.
主要成果:
- 与AHP组相比,AHP/PAC组在24小时内出现明显较低的术后疼痛 (P = .03).
- 虽然在3个月后没有注意到PA病变大小的显著差异,但AHP/PAC组从6个月开始显示出显著的减少 (P < .001).
- 在CBCT分析显示,在AHP/PAC组的一年随访后,PA损伤体积和PA体积指数显著降低 (P<.001).
结论:
- 将PAC添加到AH Plus密封剂中有效降低了手术后立即疼痛.
- 经过PAC修改的AH Plus显著增强了长期周周 (PA) 病变的愈合,从治疗后6个月观察到显著的改善.
- 这种修改后的密封剂有望改善内牙疗法对有死性肉质和牙周周炎的牙的治疗结果.
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