相关实验视频
Updated: May 13, 2025

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis
Published on: March 11, 2017
全球共识对与代谢功能障碍相关的稳定性肝病和稳定性肝炎的建议
Zobair M Younossi1, Shira Zelber-Sagi2, Jeffrey V Lazarus3
1The Global MASH Council, Washington, DC; Beatty Liver and Obesity Research Program, Inova Health System, Falls Church, Virginia.
这项研究综合了最近关于代谢功能障碍相关的脂肪性肝病 (MASLD) 和脂肪性肝炎 (MASH) 的指导方针. 它建立了共识建议,以改善患者管理和治疗实施.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 代谢障碍 代谢障碍 代谢障碍
- 临床指南 临床指南
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 和脂肪性肝炎 (MASH) 存在重大临床和经济挑战.
- 当前MASLD/MASH指南中的差异阻碍了有效的患者管理和治疗采用.
- 最近批准MASH的resmetirom强调了需要更新的共识建议的必要性.
研究的目的:
- 在最新的MASLD和MASH指南上达成共识.
- 解决因不同建议造成的混和执行差距.
- 为MASLD/MASH管理提供一套统一的建议.
主要方法:
- 一项系统的文献搜索确定了2018年1月至2025年1月期间发表的MASLD/MASH指南.
- 采用了Delphi方法,评估了8个领域的145个变量.
- 只有不到50%的一致性声明被用于达成共识,需要67%的超级多数才能被接受.
主要成果:
- 鉴定和分析了61份相关文件.
- 德尔菲进程的四轮会议产生了8份最终的共识声明.
- 所有的共识建议达成90%以上的协议,总结在表格和算法中.
结论:
- 这项研究为MASLD和MASH提供了一套全面的共识建议.
- 这些建议是从对当前指南的彻底审查和严格的共识过程中得出的.
- 这项工作旨在促进改善MASLD/MASH.患者的临床实践和患者结果.
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Published on: July 19, 2024
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