相关实验视频

Updated: May 13, 2025

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

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与白血病相关的单核酸变体的间基因转换

Alexander J Silver1, Donovan J Brown2, Sarah D Olmstead2

  • 1Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Program in Cancer Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Medical Scientist Training Program, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

Gene
|April 13, 2025
PubMed
概括

这项研究引入了CRISPR介导的基因间基因转换 (IGC),利用细胞自身的DNA逆转白血病突变. 这种方法在没有外部DNA模板的白血病模型中延长存活的希望.

关键词:
这就是CRISPR/Cas9的作用.克隆性血液形成 (clonal hematopoiesis) 是一种血液形成的过程.基因编辑 基因编辑间基因转换转换 间基因转换在白血病中,白血病.

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