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在CAD-CAM假牙树脂表面上的Candida albicans殖民

Géraldine Vetsch¹, Daniel Manoil², Claudine Wulfman³

¹Clinic of General, Special Care and Geriatric Dentistry, Center for Dental Medicine, University of Zurich, Zurich, Switzerland.

Journal of dentistry

|April 13, 2025

概括

这项研究发现,磨砂假牙树脂比3D打印或传统的PMMA树脂具有更高的Candida albicans生物膜形成率. 3D打印的树脂显示了细胞生长的增加,这表明其毒性潜力更高.

科学领域:

生物材料科学生物材料科学
微生物学微生物学
牙科假肢牙科假肢

背景情况:

牙生物膜由Candida albicans (C. albicans) 形成是一个重要的临床问题.
了解不同的假牙制造方法如何影响微生物殖民对于改善口腔卫生和患者结果至关重要.

研究的目的:

为了比较C. albicans生物膜在磨砂,3D打印和常规热聚合聚甲基甲酸 (PMMA) 假牙树脂表面上的形成.
评估制造技术对C. albicans生物膜毒性潜力的影响.

主要方法:

制造了三组假牙树脂样本 (n=27):磨砂,3D打印和热聚合的PMMA对照.
在树脂盘上生长的C. albicans生物膜被化,分离和量化.
扫描电子显微镜 (SEM) 分析生物膜形态;进行非参数测试进行统计分析.

主要成果:

对照组 (PMMA) 呈现出最低的中位生物膜附着度,具有很高的可变性.
磨砂树脂表面显示显著更高的生物膜形成与最小的变化.
与对照组相比,3D打印的树脂具有中间的生物膜附着,SEM显示了与对照组相比状树脂的增长.

结论:

制造方法显著影响C. albicans在假牙树脂上的生物膜形成.
3D打印的树脂显示了细胞生长的增加,这表明其毒性可能更高.
结果指导了牙套制造材料的选择,特别是对于高风险患者群体.

关键词:

在CAD-CAM的完整假牙.在Candida albicans中使用.数字化完整的假牙.老年人牙科老年人牙科老年牙科 - 老年牙科可拆卸的假牙是可以拆卸的.

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Candidiasis

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...