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Updated: May 13, 2025

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皮佩拉西林加剧了脏近端管道细胞中万科米辛诱导的毒性

Shingo Takada1, Yuya Takashima2, Riku Shinozaki2

  • 1Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Hokkaido University of Science, 15-4-1 Maeda 7, Teine-ku, Sapporo 006-8585, Japan.

Biological & pharmaceutical bulletin
|April 13, 2025
PubMed
概括

范科米辛 (VCM) 和皮佩拉西林/塔扎巴克坦 (PIPC/TAZ) 抗生素的组合可能会增加急性损伤 (AKI) 的风险. PIPC/TAZ直接损害细胞,恶化VCM诱导的毒性和NGAL生产,这表明增强AKI的机制.

关键词:
毒性 毒性 毒性皮佩拉西林 - 塔扎巴克坦.这就是Vancomycin.

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