在荷兰的北方马 (Fulmarus glacialis) 中高致病性禽流感
Valentina Caliendo1, Beatriz Bellido Martin2, Ron A M Fouchier2
1Dutch Wildlife Health Centre, Utrecht University, Utrecht, 3584 CL, the Netherlands.
Journal of wildlife diseases
|April 14, 2025
概括
高致病性禽流感H5病毒在荷兰的北方Fulmars被检测到. 一个亚型,H5N5,显示标记表明适应哺乳动物,突出需要持续野生动物疾病监测.
科学领域:
- 兽医病毒学 兽医病毒学
- 野生动物疾病生态学 野生动物疾病生态学
- 鸟类病原体的病原体
背景情况:
- 高致病性禽流感 (HPAI) 对全球野生鸟类种群构成重大威胁.
- 北方 (Fulmarus glacialis) 是迁徙的海鸟,可以充当禽流感病毒的储存和传播者.
- 在野生鸟群中对HPAI的监测对于早期检测和预防疫情至关重要.
研究的目的:
- 报告荷兰北方Fulmars的HPAI H5病毒感染的发现.
- 确定检测到的HPAI的特定亚型并调查任何不寻常的特征.
- 强调在野生鸟种群中持续进行传染病监测的重要性.
主要方法:
- 尸体解剖和从已故的北方富尔玛人身上取样.
- 使用RT-PCR和测序的分子检测和禽流感病毒的亚型.
- 遗传学分析以确定病毒标记物和潜在的适应性.
主要成果:
- 在2024年1月至2月期间,在荷兰发现的十名北方富尔玛死者检测出HPAI H5病毒阳性.
- 其中五只受感染的鸟类携带H5N5亚型.
- H5N5分离物表现出遗传标记,表明它们适应了哺乳动物宿主.
结论:
- 在北方Fulmars中检测到HPAI H5病毒,包括可能适应哺乳动物的H5N5亚型,强调了禽流感不断变化的威胁.
- 野生鸟类,特别是像北方富尔马这样的迁徙物种,在HPAI的流行病学中发挥着至关重要的作用.
- 持续和强大的野生鸟群传染病监测计划对于保护动物和公共健康至关重要.
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