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儿科肝移植患者肠道穿孔的频率和危险因素:一项回顾性研究
Seyyed Mohsen Dehghani1, Seyyedeh Rabie Seifi, Masoud Tahani
1From the Shiraz Transplant Research Center, Shiraz University of Medical Science, Shiraz, Iran.
概括
肠道穿孔发生在5%的儿科肝移植接受者中. 风险因素包括先前的手术,年轻年龄,体重低,和爱斯坦-巴尔病毒感染,影响生存率.
科学领域:
- 儿科手术 儿科手术
- 肝病学 肝病学是一种肝病学.
- 移植医学 移植医学
背景情况:
- 肝移植是儿科末期肝病的关键治疗方法.
- 肠道穿孔等并发症对移植接受者构成重大风险.
- 识别风险因素对于改善儿科肝移植患者的治疗结果至关重要.
研究的目的:
- 为了确定在接受肝移植的儿童中肠道穿孔的发生率.
- 在儿科接受者中识别与移植后肠道穿孔相关的风险因素.
- 为了比较儿科肝移植患者与肠道穿孔和没有肠道穿孔之间的结果.
主要方法:
- 进行了一项回顾性横截面研究.
- 分析了317名儿科肝移植接受者的数据 (2012-2020年).
- 患者被分为患有和没有移植后肠道穿孔的组.
主要成果:
- 在317名儿科肝移植患者中,16名 (5%) 患有肠道穿孔.
- 确定的危险因素包括之前的手术,年轻年龄,体重低,以及爱斯坦-巴尔病毒感染.
- 死亡率与穿孔直接相关,在经历了再穿孔的患者中,生存率为50%.
结论:
- 儿科肝移植后肠道穿孔与特定的风险因素有关.
- 早期识别风险因素,如之前的手术,年轻,低体重和EBV感染至关重要.
- 对预防策略的进一步研究是必要的,以改善患者的治疗结果.
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