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Updated: May 13, 2025

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4
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A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4

Published on: March 10, 2018

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马沃里克萨福:用于WHIM综合征的CXCR4抗剂

Canyu Chen1,2,3,4,5, Bo Xu1,2,3,4,5, Weiyi Li2,3,4,5

  • 1School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang, China.

Immunopharmacology and immunotoxicology
|April 14, 2025
PubMed
概括

治疗WHIM综合征的药物是mavorixafor (Xolremdi),这是一种CXCR4抗剂,可以增加白细胞数量,并减少12岁及以上患者的感染. 这种向治疗显示出有效性和可管理的安全性.

关键词:
在AMD07070中使用.在Cxcr4/cxcl12中使用.这就是WHIM综合征.这就是XOLREMDI.对于Mavorixa而言,这是一个很好的选择.

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