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一个便携式纸质传感器,用于同时测定人体血矩阵中的和离子

Mohammed Alqarni¹

¹Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P. O. Box 11099, Taif 21944, Saudi Arabia. m.aalqarni@tu.edu.sa.

Analytical methods : advancing methods and applications

|April 14, 2025

概括

一个新的基于纸张的传感器提供了一种低成本的便携式方法,用于同时测量人体血中的和. 这项技术可以快速分析电解质不平衡.

科学领域:

电化学电化学电化学
分析化学分析化学
材料科学材料科学材料科学

背景情况:

精确测量生物流体中的和离子对于管理健康状况至关重要.
电解质如和对于生理调节和整体健康至关重要.
现有的电解质测定方法可能是复杂的和昂贵的,用于日常的 point-of-care 使用.

研究的目的:

开发一种廉价的便携式纸质传感器,用于同时测定和离子.
为了使这些电解质直接在人体血基质中进行快速可靠的分析.
提供一个工具,以有效地管理电解质不平衡的护理点.

主要方法:

纸质传感器的制造有三个电极:一个参考电极,一个选择性电极和一个选择性电极.
利用功能化的多壁碳纳米管,选择性离子体和染料来提高传感器性能.
在人体血中测试传感器选择性,线性范围,Nernstian响应,可重现性,稳定性和响应时间.

主要成果:

传感器显示出对和离子的高选择性.
通过Nernstian响应 (斜率~59mV/十年) 实现了从10-6到10-2M的线性范围.
传感器显示可重复和稳定的潜力超过180天,快速10秒的响应时间.

结论:

开发的基于纸张的传感器是一种简单,具有成本效益和一次性工具,用于 Point-of-care 分析.
它可以快速可靠地同时确定人体血中的和.
这种传感器代表了在临床环境中管理和失衡的宝贵进步.

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