在肺结核患者中开发和验证用于预测肺栓塞的诺姆图
Haobo Kong1, Yingying Sang1,2, Jingjing Pan1
1Department of Respiratory Intensive Care Unit, Anhui Chest Hospital, Hefei, China.
Journal of thoracic disease
|April 14, 2025
概括
这项研究开发了一种名谱,用于预测肺结核 (PTB) 患者的肺栓塞 (PE). 该模型使用诸如D-二次数和胸痛等因素,显示了早期诊断和风险评估的高准确性.
科学领域:
- 肺部医学 肺部医学
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
背景情况:
- 肺结核 (PTB) 和肺栓塞 (PE) 的共存是罕见的,但与高死亡率有关.
- 由于相关风险,在PTB患者中早期诊断PE至关重要.
研究的目的:
- 开发和验证一种名谱模型,用于预测诊断为PTB的患者的PE风险.
- 改善这种不常见的并发症的早期检测和管理策略.
主要方法:
- 使用694名PTB患者 (发育队列) 的数据开发了一个预测模型,并在236名PTB患者 (验证队列) 中验证.
- 确定了独立的风险因素,并使用ROC曲线分析 (AUC),校准曲线和决策曲线分析 (DCA) 评估了名录表的表现.
主要成果:
- 确定的主要独立风险因素包括D-二次体,年龄,瘤,胸痛,呼吸障碍和手术.
- 诺米图实现了高预测准确度,AUC值为0.903 (发展) 和0.821 (验证).
- 校准曲线和DCA证实了该模型强大的预测能力和临床实用性.
结论:
- 开发的诺莫格拉姆模型在评估PTB患者的PE风险方面表现出高的预测准确性.
- 这种工具为结核病患者的风险分层和及时干预提供了重要的临床价值.
相关概念视频
Pulmonary Tuberculosis IV
123
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
123
Pulmonary Tuberculosis II
201
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
201
Pulmonary Tuberculosis III
267
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
267
Pulmonary Tuberculosis V
157
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
157
Pulmonary Tuberculosis I
208
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
208


