优化牙植入物设计:结构,强度和骨内生长.
Jenny Zwei-Chieng Chang1,2, Jui-Ting Hsu3,4,5, Ming-Jun Li6
1School of Dentistry, College of Medicine, National Taiwan University, Taipei, Taiwan.
Journal of dental sciences
|April 14, 2025
概括
牙植入物的多孔性会影响骨的生长和稳定性. 较低的多孔设计促进骨再生和强度,这对于预防周植入炎和确保长期假肢成功至关重要.
科学领域:
- 生物材料科学是生物材料的科学.
- 牙科植入物学 牙科植入物学
- 生物力学 生物力学
背景情况:
- 牙植入物周围的功能诱导的骨损失可以使牙周植入炎恶化.
- 识别影响边际骨损失的因素对于植入成功至关重要.
研究的目的:
- 通过有限元素 (FE) 模拟和体外分析来评估牙植入物设计概念.
- 评估植入物设计对植入物和周围骨的应力和应变的影响.
主要方法:
- 对五种植入物设计的分析:全固体,上层多孔,下层多孔,下层多孔:上半部分,下层多孔:下半部分.
- 包括稳定性测量,3D FE建模,体外机械测试和骨改造模拟.
主要成果:
- 完全坚固的设计表现出最高的应力耐受性,其次是下部和上部多孔的设计.
- 斜力增加了应力度;上层多孔的设计显示出有利的骨压力,但强度有限.
- 较低的多孔植入物与完整的固体强度相匹配,并增强了边缘骨生长.
结论:
- 精心设计的多孔结构可以改善植入后的骨生长.
- 上层多孔的设计有助于骨内生长,但强度降低;下层多孔性对骨再生产生负面影响.
相关概念视频
Bone Structure
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
Bone Formation by Intramembranous Ossification
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Bone Remodeling and Repair
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...


