过度表达MiR-146b通过SMAD4/C-MYC/Cyclin D1轴促进了膀癌细胞的生长

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Updated: May 13, 2025

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Junlan Zhu1, Zhijian Zheng2, Zhangya Yin1

  • 1Precision Medicine Laboratory, Beilun People's Hospital, Beilun Branch of the First Affiliated Hospital, School of Medicine, Zhejiang University, Ningbo, Zhejiang, China.

Frontiers in oncology
|April 14, 2025
PubMed
概括

降低调节的microRNA-146b (miR-146b) 通过阻止细胞循环来抑制人类膀癌 (BCa) 的生长. 这通过一种新的SMAD4/C-MYC/Cyclin D1途径发生,为BCa.提供潜在的治疗点.

关键词:
在C-MYC中.环 D1 环 D1 是一种在 MiR-146bb 系统中.在SMAD4中,我们可以看到SMAD4.膀癌细胞生长的原因

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