印度第三级护理中心的抗菌素处方模式:一个多中心点流行调查
Samiksha Bhattacharjee1, Chakrant Mothsara2, Nusrat Shafiq2
1AIIMS Deoghar, India.
EClinicalMedicine
|April 14, 2025
概括
这项研究发现,印度医院的抗生素使用量很高,氏和社区感染很常见. 需要采取干预措施来改善抗微生物药物管理和减少耐药性.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 临床药房 临床药房
背景情况:
- 抗菌素耐药性 (AMR) 是一个重大的全球健康挑战.
- 点患病率调查 (PPS) 对于了解抗生素消耗和耐药性模式至关重要.
- 印度的三级护理医院面临AMR日益增长的威胁.
研究的目的:
- 评估印度三级医院的抗生素使用模式和耐药性.
- 为开发有针对性的抗微生物管理干预提供数据.
- 为印度打击抗微生物药物耐药性的战略提供信息.
主要方法:
- 在印度八家三级医院进行了两周的横截面调查.
- 通过病房和患者表格收集的数据,包括人口统计,抗菌药物治疗和微生物学的数据.
- 评估抗生素使用的合理性,通过训练有素的测量人员进行数字数据收集.
主要成果:
- 成人手术和儿科病房的抗生素使用率最高.
- 塞夫特里亚克松,美特罗尼达和阿米卡是最常被处方的抗生素.
- 医院获得感染 (HAI) 的患病率为13.3%,经验使用占主导地位;常见的隔离物包括大肠杆菌和肺炎.
- 抗生素使用的合理性差异很大,长期预防/治疗是关键问题.
结论:
- 该调查强调了印度第三级护理中心大量使用抗生素.
- 迫切需要强有力的抗菌药物管理计划和持续的抗菌耐药性监测.
- 完善处方实践,针对HAI,减少不必要的治疗对于AMR控制至关重要.
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