长期细菌性支气管炎的婴儿的临床特征:一项观察性队列研究
Yaping Xie1, Chen Chen1, Diyuan Yang1
1Department of Respiration, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Translational pediatrics
|April 14, 2025
概括
长期的细菌性支气管炎 (PBB) 在婴儿中经常出现湿咳和喘息. 早期诊断和抗生素治疗导致大多数患有 PBB 的婴儿的康复.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 肺部病理学 肺部病理学
背景情况:
- 长期细菌性支气管炎 (PBB) 是一个未被认可的婴儿疾病.
- 关于其临床特征和诊断成像的数据有限.
- 本研究旨在确定PBB的早期检测特征.
研究的目的:
- 为了确定婴儿PBB的临床表现.
- 描述与 PBB 相关的成像发现.
- 为了促进 PBB 的早期诊断和管理.
主要方法:
- 预计从2021年1月到2024年1月将有37名婴儿在联合国儿童基金会注册.
- 收集临床数据,实验室参数和放射学发现.
- 进行了支气管镜检查和支气管膜洗 (BAL) 培养物.
主要成果:
- 所有婴儿都出现了湿咳; 91.89%的婴儿有持续的喘息.
- 常见的病原体包括莫拉塞拉细菌和肺炎链球菌.
- 胸部CT最频繁地显示不均的膨胀;支气管镜检查显示厚的粘液.
结论:
- 喘息是婴儿PBB的关键临床症状之一.
- 莫拉塞拉菌和肺炎链球菌是流行病原体.
- 在CT扫描上不均的通货膨胀表明 PBB.
相关概念视频
Pulmonary Cycle: Exhalation
1.3K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
1.3K
Pneumonia I: Introduction
190
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
190
Chronic Obstructive Pulmonary Disease-I: Introduction
2.7K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.7K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
Chronic Obstructive Pulmonary Disease
1.1K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.1K
Pneumonia III: Complications and Assessment
123
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
123


