多种维生素与成年男性的精子质量之间的联合和个体关联
Wen Yao1, Juan Zhang1, Weihong Yan1
1Reproductive Medicine Center, General Hospital of Central Theater Command, Wuhan, Hubei, China.
Frontiers in nutrition
|April 14, 2025
概括
维生素B1和维生素D可以提高精子质量,而维生素B12和维生素A则表现出不同的效果. 个性化的维生素摄入量,考虑到类型和剂量,可能是男性生育能力的关键.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 营养科学 营养科学
- 男人不孕症研究研究
背景情况:
- 饮食习惯显著影响男性生殖健康.
- 各种维生素对精子参数的具体影响需要进一步阐明.
研究的目的:
- 检查血清维生素度与男性精子质量关键指标之间的关系.
- 区分单个维生素对男性生育能力的影响与组合维生素状态的影响.
主要方法:
- 对156名接受生育评估的男性进行横截面分析.
- 测量了9种血清维生素和5种精子质量指标,包括DNA碎片化指数.
- 使用多重线性回归和贝叶斯核机器回归 (BKMR) 的统计建模.
主要成果:
- 较高的血清维生素B1和1,25-二氧维生素D3水平与精子质量的改善有关.
- 增加的维生素B12与增加的精子DNA碎片化相关,而维生素A与渐进性运动有负面关联.
- 结合维生素水平和精子参数之间的BKMR模型通常表示无关联.
结论:
- 维生素可能对精子质量产生剂量依赖的双重影响,因类型和度而异.
- 个性化维生素补充策略可能比一般的多种维生素对男性生育能力提供更大的好处.
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