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Updated: May 13, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
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Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

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与基于人口的病例相比,在三个多病例家族中,多原性多发性硬化症的风险没有得到丰富

Ming Chen1,2, Allan Motyer3,4,5, Bruce V Taylor1

  • 1Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.

Human mutation
|April 14, 2025
PubMed
概括

多发性硬化症 (MS) 风险在有多例病例的家庭中较高,但这种遗传风险并不能完全解释MS在家庭中的聚类. 与一般人群相比,在受影响和未受影响的家庭成员中观察到多基因风险增加.

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