与OTOF基因相关的听力神经病变的发病和研究进展:回顾性审查

Jiang-Hui Yang1, Duo-Mi Zhang1, Kai Wang2

  • 1Health Science Center, Ningbo University Ningbo, Zhejiang, China.

概括

与OTOF基因相关的听觉神经病 (AN) 通过破坏内毛细胞功能来影响听力. 本综述探讨了导致AN的奥托费林基因突变及其对语音理解的影响.

相关概念视频

Hearing01:31

Hearing

When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
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The Cochlea01:13

The Cochlea

The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
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Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

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Auditory Pathway01:15

Auditory Pathway

Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
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