在全球范围内追踪和分析良性前列腺增生和前列腺癌负担:1990-2021年流行病学趋势
Qizhou Mo1, Fengyi Wang2, Haiqi Liang1
1Department of Urology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Translational andrology and urology
|April 14, 2025
概括
在全球范围内,良性前列腺增生症 (BPH) 和前列腺癌 (PCa) 发病率显著上升. 虽然PCa是一个PCa.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 良性前列腺增生 (BPH) 和前列腺癌 (PCa) 在老年男性中很常见.
- 目前全球BPH和PCa的流行病学数据有限.
研究的目的:
- 从1990年到2021年全面评估全球BPH和PCa的发病率,残疾调整寿命 (DALYs) 和死亡率.
- 分析与这些前列腺疾病相关的趋势和风险因素.
主要方法:
- 利用了来自2021年全球疾病负担数据库的数据.
- 分析了BPH和PCa的发病率,DALY,死亡率和可归因的风险因素.
- 计算了年龄标准化利率的估计年均百分比变化 (EAPC),并检查了与社会人口指数 (SDI) 的相关性.
主要成果:
- 从1990年到2021年,BPH和PCa发病率分别增加了115.23%和161.66%.
- 前列腺癌显示年龄标准化死亡率和DALY率下降 (EAPC =-0.68和-0.83).
- 东欧/亚洲的BPH负担最高;PCa负担集中在高收入地区. 与吸烟相关的PCa DALY和死亡率下降.
结论:
- BPH和PCa对全球健康构成重大和日益增长的挑战.
- 战略性资源配置至关重要,考虑到BPH和PCa流行病学的区域差异.
- 尽管PCa的相对负担正在下降,但绝对负担需要持续关注.
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