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Updated: May 13, 2025

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由寡头细胞衍生的IL-33调节中枢神经系统自身免疫中的自反应性CD8+T细胞

Nicolas Fonta1, Nicolas Page1,2, Bogna Klimek1

  • 1Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.

The Journal of experimental medicine
|April 14, 2025
PubMed
概括

来自寡头细胞的IL-33驱动慢性中枢神经系统自身免疫性疾病,通过促进自我反应性CD8+T细胞的存活和分化. 阻断IL-33治疗性地减少炎症和改善疾病,识别组织因素作为新型免疫标.

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