用GABALAGEN®针对老化皮肤:一种通过人类随机试验验证的协同作用的海洋营养美容成分
Jimin Hyun1, Kyoung-Min Rheu2, Bae-Jin Lee2
1Department of Food Science & Nutrition, Pukyong National University, Busan 48513, Republic of Korea.
Antioxidants (Basel, Switzerland)
|April 14, 2025
概括
加巴拉根 (GBL),一种含有鱼类原和发酵胺酸 (GABA) 的海洋成分,改善了皮肤水分和减少了成年人的纹. 这种可持续的营养化品没有显示任何不良影响,并显示出抗氧化和抗炎性质.
科学领域:
- 海洋生物技术 海洋生物技术
- 营养保健品 营养保健品
- 皮肤病学 皮肤病学
背景情况:
- 老化皮肤的特点是水分减少,纹深度增加,弹性降低.
- 海产的原蛋白和胺黄油酸 (GABA) 已被认为具有潜在的健康益处.
- 可持续的采购和创新的加工对于开发有效和环保的功能成分至关重要.
研究的目的:
- 评估GABALAGEN (GBL) 的有效性和安全性,这是一种新的海洋衍生成分,对皮肤衰老的参数.
- 研究GBL的体外抗氧化和抗炎作用.
- 突出GBL对营养化品行业可持续创新的贡献.
主要方法:
- 一个为期12周的随机,双盲,安慰剂对照试验,涉及100名年龄在35-60岁的成年人.
- 参与者每天消耗1500毫克的果形式的GBL.
- 在实验室中对UVB辐射的角质细胞进行了测试,以评估抗氧化和抗炎活性.
主要成果:
- 显著改善皮肤水分 (+20%) 和减少纹深度 (-15%) 在GBL组观察到第12周.
- 观察到皮肤密度和弹性的提高,没有报告的不良影响.
- 实验室研究表明,GBL具有强烈的抗氧化剂 (超氧化解突变酶活性) 和抗炎作用 (减少促炎细胞因子).
结论:
- 加巴拉根 (GBL) 是一种有效的营养化品成分,可以改善老化皮肤,在水分和减少纹方面具有显著的益处.
- 发酵过程提高了GABA的生物可用性和抗氧化能力,确保了安全性和有效性.
- GBL代表了从渔业副产品中获得的可持续,高价值产品,与循环经济原则保持一致,并在功能成分方面取得了突破.
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