六天禁食导致健康年轻男性抗氧化能力和氧化应激的临时增加:一项随机对照试验
Marius Brazaitis1, Katerina Židonienė1, Nerijus Eimantas1
1Institute of Sport Science and Innovations, Lithuanian Sports University, 44221 Kaunas, Lithuania.
Antioxidants (Basel, Switzerland)
|April 14, 2025
概括
长时间的禁食会增加健康男性的氧化应激 (OS) 和抗氧化防御,但保持氧化还原平衡. 这些变化,包括更高的子和更低的丸激素,在重新养后恢复正常.
科学领域:
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
- 氧化压力研究研究 氧化压力研究
背景情况:
- 长时间禁食对氧化应激 (OS) 和抗氧化机制的影响尚未得到充分证实.
- 了解身体对禁食的氧化还原反应对于代谢健康的洞察至关重要.
研究的目的:
- 为了研究健康男性6天完整禁食期间的氧化还原状态和交感神经系统活动.
- 评估长时间禁食对基质氧化,激素和氧化应激标志物的影响.
主要方法:
- 一项随机对照试验,涉及26名健康男性,他们进行了为期6天的完全禁食或控制饮食.
- 监测同情活性,基质氧化,血糖,,,马隆迪 (MDA) 和总抗氧化能力 (TAC).
主要成果:
- 禁食导致体增加,脂肪氧化和甲 (MDA) 水平增加.
- 在禁食期间观察到碳水化合物氧化,葡萄糖和丸激素度的降低.
- 总抗氧化能力 (TAC) 与MDA一起增加,保持恒定的TAC/MDA比率,表明平衡的氧化还原状态.
结论:
- 六天的禁食会激活氧化应激和抗氧化防御系统,但身体的氧化还原平衡会保持.
- 禁食引起的代谢和荷尔蒙标记的变化,包括增加和同情活性,以及降低丸激素,在恢复正常饮食后是可逆的.
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