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Updated: May 13, 2025

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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在新设计的平行和反平行A3B3 Heterohexameric α-螺旋桶

Joel J Chubb1,2, Katherine I Albanese1,3, Alison Rodger4

  • 1School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, U.K.

Biochemistry
|April 14, 2025
PubMed
概括

设计新的alpha-helical卷轴组件,如A3B3桶,现在是可能的. 序列寄存器意外地控制了螺旋体的方向和组装,影响了蛋白质建模.

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