在初级保健中接受治疗的成年人的数字抑郁症治疗计划:一项随机临床试验
Jennifer Dahne1,2, Amy E Wahlquist3, Matthew J Carpenter1,2
1Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston.
JAMA internal medicine
|April 14, 2025
概括
一种数字行为激活干预,Moodivate,显著改善了初级保健患者的抑郁症症状. 这种可扩展的数字心理健康工具为中度抑郁症的成年人提供了有效的治疗选择.
科学领域:
- 数字健康干预措施 数字健康干预措施
- 行为激活疗法是一种行为激活疗法.
- 初级保健 心理健康 心理健康
背景情况:
- 在美国,有超过三分之二的患有抑郁症症状的成年人在初级保健中没有接受治疗.
- 需要在初级保健机构对抑郁症进行可扩展,基于证据的干预措施.
研究的目的:
- 评估Moodivate的有效性,这是一种自我指导的数字干预,用于治疗初级保健患者的抑郁症症状.
- 为了比较Moodivate带有和没有EHR整合与常规护理.
主要方法:
- 一个三组,分散的随机临床试验,涉及中度抑郁症状 (PHQ-9分数≥10) 的成人初级保健患者.
- 干预措施包括Moodivate (数字行为激活),Moodivate与提供商的EHR访问以及通常的护理.
- 主要结局是12周内使用贝克抑郁 inventory-II (BDI-II) 测量抑郁症状的变化.
主要成果:
- 与通常的护理相比,Moodivate两组的参与者在抑郁症症状中表现出显著更大的改善.
- 情绪变化组的临床显著改善几率高2.5至3.0倍,抑郁症缓解几率高2.3至2.6倍.
- 观察到高参与度,33%的患者在12周后继续使用Moodivate.
结论:
- 数字行为激活干预 (Moodivate) 在初级保健中有效治疗中度抑郁症状的成年人.
- 这种数字方法提供了一个可扩展和基于证据的解决方案,用于改善初级保健机构的心理健康结果.
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