夜间戴完整假牙和阻塞性睡眠呼吸暂停:一个元分析
Sunit Kumar Jurel1, Husbana Altaf Bakrolwala, Pooran Chand
1Department of Prosthodontics, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India.
Journal of Indian Prosthodontic Society
|April 14, 2025
概括
夜间佩戴可拆卸的全牙假牙并没有显著改善阻塞性睡眠呼吸暂停 (OSA) 的结果. 这次审查发现,没有足够的证据支持其在治疗OSA症状方面的有效性.
科学领域:
- 睡眠医学 睡眠医学
- 牙科 睡眠医学 睡眠医学
- 临床研究方法论 临床研究方法论
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 管理可能通过评估夜间假牙磨损等干预措施来改善.
- 对于OSA患者来说,一夜之间佩戴可拆卸的全牙假牙的有效性仍然是一个悬而未决的问题.
研究的目的:
- 系统地审查和分析现有文献,比较夜间可拆卸全牙假牙或Overenture在OSA患者中的使用效果.
- 关键的结果指标包括呼吸暂停-低音指数 (AHI),爱普沃思睡眠度量表 (ESS) 和匹兹堡睡眠质量指数 (PSQI).
主要方法:
- 一个系统审查协议被注册在一个开源注册表.
- 控制试验的Medline,Embase和Cochrane中央注册表的搜索一直持续到2024年8月.
- 数据提取和偏差风险评估由独立审查员进行,使用固定效应模型和GRADE方法进行统计分析,以确保证据的确定性.
主要成果:
- 包含了三项随机对照试验,共有123名参与者.
- 在夜间戴假牙和非戴假牙之间,无呼吸-低呼吸指数 (AHI) 中没有发现显著差异 (MD: 2.88).
- 同样,对于匹兹堡睡眠质量指数 (PSQI) (MD:0.20) 或爱普沃思睡眠度量 (ESS) (MD:0.20) 也没有发现显著差异.
结论:
- 目前的证据不足以得出结论,夜间佩戴可拆卸的全牙假牙对阻塞性睡眠呼吸暂停患者有效.
- 需要进一步进行高质量的研究,以最终评估这项干预对OSA参数的好处.
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