偶发性体力活动对心血管事件和死亡率的剂量反应
Emmanuel Stamatakis1,2, Raaj K Biswas1,2, Nicholas A Koemel1,2
1Mackenzie Wearables Research Hub, Charles Perkins Centre (E.S., R.K.B., N.A.K., A.S., M.N.A.).
Circulation
|April 14, 2025
概括
偶尔的体力活动 (IPA),包括强烈的 (VIPA) 和中度的 (MIPA) 强度,显著降低心血管风险和死亡率. 即使是少量的VIPA或MIPA也能为健康带来巨大的好处,
科学领域:
- 心脏病学
- 公共卫生
- 运动科学
背景情况:
- 中年和老年人炼时间有限.
- 偶尔体育活动 (IPA) 是增加日常运动的替代方案.
- 缺乏IPA干预和指导方针的剂量反应数据.
研究的目的:
- 检查设备评估的IPA强度 (强烈[VIPA],中度[MIPA],轻度[LIPA]) 与主要心血管不良事件 (MACE) 和死亡率之间的关联.
- 估计LIPA和MIPA相对于VIPA的"健康等价性".
主要方法:
- 来自英国生物库加速度计子研究 (年龄为61.9±7.6岁) 的24139名不运动者的分析.
- 使用基于机器学习的强度分类器计算IPA能源消耗和每日持续时间.
- 预期队列设计与MACE,心血管疾病死亡率和全因死亡率的随访.
主要成果:
- IPA体积与降低的MACE,心血管疾病死亡率和全因死亡率有着L形的关联.
- 任何VIPA或MIPA与较低的风险有关,最佳益处在每天14分钟 (VIPA) 和每天34-50分钟 (MIPA) 左右.
- 在心血管风险降低方面,一分钟的VIPA相当于MIPA的2. 8- 3. 4分钟或LIPA的34. 7- 48. 5分钟.
结论:
- 每天偶尔的体力活动,特别是强烈和中等强度的体力活动,与心血管风险的降低有关.
- 光强度IPA显示较弱的关联,仅对较长时间的心血管疾病死亡率有意义.
- IPA为改善心血管健康提供了一个有价值的策略,
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