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Updated: May 16, 2025

A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening
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A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening

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一个可光激活的自由酸探针,用于研究菌根菌与宿主相互作用

Kingsley C Agu1, Nicholas Banahene1,2, Carolina Santamaria3

  • 1Department of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.

ACS infectious diseases
|April 14, 2025
PubMed
概括

来自Mycobacterium tuberculosis的自由酸 (fMA) 是免疫逃避的关键. 研究人员开发了一种新型探针来识别fMA相互作用蛋白质,揭示TREM2是关键宿主免疫受体.

关键词:
菌根细菌 (Mycobacteria) 是一种细菌.然后点击化学.免疫学 免疫学 免疫学巨细胞是什么?巨细胞是什么?醇酸是什么意思? 醇酸是什么意思?的外膜外膜.摄影亲和关系 (photoaffinity) 是一种对照片的亲和关系.综合合成是一种合成.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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