在FOXP4中Cis-regulatory的改变调节由慢性酒精暴露引起的食道癌易感性

Siyuan Niu1, Jialing Ma1, Shasha Liu1

  • 1Huazhong University of Science and Technology, Wuhan, Hubei, China.

Cancer research
|April 14, 2025
PubMed
概括

长期使用酒精会增加食道状细胞癌 (ESCC) 的风险. 一种特定的FOXP4基因变异 (rs10223516) 与酒精相互作用,通过改变基因表达,显著提高ESCC易感性和瘤生长.

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