研究热点和边界分析在骨质疏松症相关领域的门德尔随机化:基于文献计量和视觉分析的审查
Qingqing Zeng1,2, Sijie Gui3, Zhuolan Li1
1School of Nursing, University of South China, Hengyang, China.
Medicine
|April 14, 2025
概括
骨质疏松症 (OP) 的门德尔随机化 (MR) 研究正在增长,中国领导高影响力研究. 未来的趋势表明将MR与临床和观察数据相结合,以获得更深入的见解.
科学领域:
- 生物医学研究的研究.
- 遗传学 遗传学 是一个
- 流行病学 流行病学
背景情况:
- 骨质疏松症 (OP) 是一个重要的全球健康问题.
- 门德尔随机化 (MR) 是一种越来越多地用于研究OP的因果关系的方法.
- 了解OP中MR的当前研究环境对于未来的进展至关重要.
研究的目的:
- 在骨质疏松症 (OP) 相关领域全面分析孟德尔随机化 (MR) 的当前状态和研究热点.
- 为OP提供MR未来的研究方向提供参考.
- 确定该研究领域的领先国家,机构和期刊.
主要方法:
- 2007年1月1日至2024年3月15日的出版物的图书统计和视觉分析,来源于科学网络核心集合.
- 使用CiteSpace和VOSviewer分析引用统计,作者,期刊,出版年份,国家和关键字的共同出现.
- 研究了出版量,研究热点和跨学科整合的趋势.
主要成果:
- 从2007年到2024年,在OP相关领域对MR的出版物持续增加.
- 中国,美国和英国是高影响力出版物的领先国家.
- 关键的研究热点包括风险因素,全基因组关联,元分析,骨折和基因位置,重点关注与OP的因果关系.
结论:
- 门德尔的随机化是骨质疏松症研究的一个快速发展的领域,中国,美国和英国都有着重要的贡献.
- 目前的研究重点是确定风险因素和骨质疏松症之间的因果关系.
- 预计未来的研究将强调跨学科的整合,将MR与临床试验和观察性研究结合起来.
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