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Updated: May 23, 2025

Development of an Antigen-driven Colitis Model to Study Presentation of Antigens by Antigen Presenting Cells to T Cells
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Published on: September 18, 2016

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对肠道抗原产生耐受性的PRDM16依赖性抗原呈现细胞

Liuhui Fu1, Rabi Upadhyay1,2, Maria Pokrovskii1,3

  • 1Department of Cell Biology, New York University School of Medicine, New York, NY, USA.

Nature
|April 14, 2025
PubMed
概括

研究人员发现了一种新的免疫细胞类型,PRDM16+RORγt+耐受性树突细胞 (tolDCs),对口服耐受性至关重要. 这些细胞防止对食物和微生物的炎症反应, 为过敏和自身免疫性疾病提供潜在的治疗点.

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