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Updated: May 3, 2026

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
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Published on: March 23, 2011

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长期使用哈洛佩里多尔治疗在转基因动物模型中调节血管酶I转化酶 (ACE) 活性,具有对精神分裂症研究的构造有效性

William Y Oyadomari1, Thays C Santiago1, Leonardo Basso1

  • 1Department of Pharmacology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil.

Brain research
|April 14, 2025
PubMed
概括

在未服用过药物的老鼠中,血管素I转化酶 (ACE) 活性升高反映了精神病的发现. 抗精神病治疗改变了大脑ACE不同于血清ACE,表明有不同的中央和外周系统.

关键词:
动物模型动物模型生物标志物生物标志物在 DISC1 中.这是一种多巴胺阻断剂.类酸酶的存在转基因的转基因

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