生物聚合物对食源性病原体的抗菌潜力:一篇更新的评论
Anowar Khasru Parvez1, Fatema Tuz Jubyda1, Joyoshrie Karmakar1
1Department of Microbiology, Jahangirnagar University, Savar, Dhaka, Bangladesh.
Microbial pathogenesis
|April 14, 2025
概括
来自植物,微生物和动物的生物聚合物对抗药物耐药性食品传播病原体表现出抗菌活性. 这些天然化合物为传统抗微生物药物提供了有希望的替代品,向微生物细胞结构和功能.
科学领域:
- 生物化学和微生物学
- 自然产品化学 自然产品化学
背景情况:
- 抗微生物耐药性是一个日益增长的全球健康威胁.
- 传统的抗微生物药物在对抗耐药性病原体方面面临着挑战.
- 生物聚合物由于其固有的抗微生物特性,提供了潜在的替代品.
研究的目的:
- 审查来自各种来源 (植物,微生物,动物) 的生物聚合物.
- 突出它们对抗食物传播病原体的抗微生物应用.
- 阐明它们的作用机制.
主要方法:
- 关于生物聚合物及其抗菌作用的科学研究的文献综述.
- 对生物聚合物来源,类型及其对特定食品传播病原体的有效性进行分析.
- 检查已记录的抗微生物机制.
主要成果:
- 生物聚合物如纤维素,粉,酸盐和凝表现出抗菌活性.
- 它们对一系列食源性病原体有效,包括沙门氏菌,大肠杆菌和金黄色葡萄球菌.
- 机制包括细胞壁/膜的破坏,DNA损伤和干扰定数感应.
结论:
- 生物聚合物代表了一类有前途的天然抗菌剂.
- 它们可以作为对抗耐药性食品传播病原体的常规药物的可行替代品.
- 对生物聚合物结合的进一步研究可能会提高它们的有效性.
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