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在住院期间个人连续葡萄糖监测器的现实世界性能
Adrian G Dumitrascu1, Michelle Perry2, Ana-Maria Chindris2
1Division of Hospital Internal Medicine, Mayo Clinic Florida, Jacksonville, Florida, USA.
Diabetes technology & therapeutics
|April 14, 2025
概括
患者的个人持续血糖监测器 (CGM) 显示出足够的医院准确性,除了低血糖症. 生命体征和实验室值没有影响CGM的表现,这表明可靠的住院血糖监测.
科学领域:
- 内分泌学 在内分泌学.
- 医疗器械 医疗器械
- 糖尿病管理 糖尿病管理
背景情况:
- 连续血糖监测器 (CGM) 越来越多地用于糖尿病管理.
- 在住院治疗中评估CGM准确性对于患者安全和有效的血糖控制至关重要.
研究的目的:
- 评估患者在医院环境中使用的个人CGM的准确性.
- 确定CGM准确度与实验室葡萄糖值以及生命体征之间的相关性.
- 将住院患者的CGM性能指标与已发表的文献和临床指南进行比较.
主要方法:
- 在入院时使用个人CGM的糖尿病成年患者被纳入非临界护理环境.
- CGM读数与照顾点 (POC) 葡萄糖计和实验室 (实验室) 血糖测量时间配对.
- 使用平均绝对相对差异 (MARD) 和克拉克错误网格来评估准确性;对生命体征和实验室值进行了相关性分析.
主要成果:
- CGM-POC对产生了13.7%的MARD (Dexcom: 14.4%,Libre: 11.8%),而CGM-Lab对显示了13.6%的MARD (Dexcom: 12.7%,Libre: 15.4%). 这两种组的MARD值均为1.3%.
- 在克拉克错误网格上,超过98%的CGM-POC和CGM-Lab对位于可接受区域 (A和B) 之内.
- 没有发现CGM准确度与平均动脉血压,血红蛋白,淋巴膜过率或脉冲氧计之间的显著相关性.
结论:
- 个人CGM显示出足够的准确性用于住院血糖监测,在低血糖范围中指出了限制.
- 住院患者的CGM性能不受生命体征或实验室结果的显著影响.
- 观察到的时间范围 (TIR) 和葡萄糖可变度指标与住院患者的指导方针保持一致,并且与医院插入的传感器可比.
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