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在海地的一个基于人口的队列中,成年人中的左心室缩
Anju Ogyu1, Vanessa Rouzier2, Rodney Sufra2
1Center for Global Health, Weill Cornell Medicine, New York City, NY, USA. ano4011@med.cornell.edu.
Scientific reports
|April 14, 2025
概括
左心室缩 (LVH) 在高风险的海地成年人中很常见. 心声学 (TTE) 在诊断 LVH 方面优于心电学 (ECG),突出了在资源有限的环境中需要更好的诊断工具的需要.
科学领域:
- 心脏病学 心脏病学
- 医学诊断 医学诊断 医学诊断
- 公共卫生 公共卫生
背景情况:
- 左心室缩 (LVH) 是心血管疾病 (CVD) 和死亡率的重要预测因素.
- 在资源有限的环境中,LVH的诊断方法有限.
- 高风险人群需要可访问和准确的LVH查.
研究的目的:
- 在海地高风险成年人群中使用跨胸腔心声扫描 (TTE) 确定LVH的患病率.
- 为了比较TTE与心电图 (ECG) 检测LVH的诊断准确度.
- 评估用抗高血压药物对确诊的LVH病例的管理.
主要方法:
- 来自海地心血管疾病队列研究 (n=3,005) 的入学数据的分析.
- 参与者接受了问卷,生命体征,身体检查和12个心电图.
- 在1040名患有高血压或心血管疾病症状的参与者身上进行了胸外回声心脏成像 (TTE),在ASE指导方针中定义了LVH.
主要成果:
- 经过TTE诊断的LVH的患病率为39.0% (95% CI 36.6-41.5%),与年龄较大有关.
- 只有26%的TTE-LVH患有高血压的患者接受了抗高血压药.
- 与TTE相比,基于心电图的LVH检测显示出低一致性 (κ < 0.20),低敏感性 (<10%),高特异性 (> 90%).
结论:
- 在高风险的海地成年人中, LVH 的患病率很高,这强调了需要有效的诊断策略的需要.
- 电心电图 (ECG) 在这个人群中显示了与TTE相比,对LVH检测的敏感性较差.
- 对被诊断为TTE的LVH患者进行抗高血压治疗可能会减轻心血管疾病不良后果的风险.
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