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Updated: May 13, 2025

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

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KDM5A/HOXA5轴通过激活Wnt/β-catenin通路来调节骨髓瘤的进展

Yi Luo1, Youzhi He2, Yuxia Xu2

  • 1Department of Spine Surgery, Hengyang Medical School, The Affiliated Changsha Central Hospital, University of South China, The No.161 of the Shaoshan South Road, Changsha City, Hunan Province, China. luoyi8166@126.com.

European journal of medical research
|April 14, 2025
PubMed
概括

氨酸特异性去甲基酶5A (KDM5A) 通过抑制Homeobox A5 (HOXA5) 来驱动骨肉瘤的进展. 向KDM5A抑制瘤生长并激活HOXA5,影响治疗潜力的Wnt/β-catenin通路.

关键词:
lysine 4 在 histone H3 上的二甲基和三甲基化.主页obox A5 A5 的位置.氨酸特异性脱甲基酶5A 氨酸特异性脱甲基酶5A甲基化修改的方法骨质肉瘤骨质肉瘤是什么

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