不知初级的侵袭性状细胞癌:孤立的内转移和不常见的进展
Beril Balci Topuz1, Mustafa Seyyar2, Meltem Ozturk Iyilikci1
1Department of Radiation Oncology, Gaziantep City Hospital, Gaziantep, Turkey.
The American journal of case reports
|April 15, 2025
概括
未知初级癌症 (CUP) 呈现为 inguinal 淋巴结转移,即使在状细胞癌 (SCC),也可能是侵略性的. 这一案例凸显了潜在加强多式联络治疗的必要性,以更好地控制疾病.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 未知原发性癌 (CUP) 是一种罕见的癌症,占所有恶性瘤的<5%.
- 内淋巴结 (LN) 转移是一种不常见的CUP表现.
- 状细胞癌 (SCC) 仅占CUP病例的一小部分.
研究的目的:
- 报告一个罕见的CUP病例与孤立的 inguinal LN转移.
- 讨论这次演讲的攻击性行为和治疗挑战.
- 强调需要重新评估治疗方案的必要性.
主要方法:
- 一个65岁妇女的病例报告,患有未知初级SCC.
- 诊断工作包括PET-CT.
- 通过手术治疗,使用思普拉丁的化疗放射治疗 (CRT),使用思普拉丁和5-甲的化疗.
主要成果:
- 在没有发现原发性瘤的情况下,在 inguinal LN 中初步诊断出 SCC.
- 疾病复发和进展到肺和阴部转移尽管CRT.
- 在右乳房中发现了新的转移性病变,这是此前未经记录的网站.
- 患者在诊断后12个月因呼吸道并发症而死亡.
结论:
- 从未知初级的SCC中分离的 inguinal LN转移可以表现出侵略性行为.
- 当前的治疗策略可能需要对这些具有挑战性的CUP病例进行重新评估.
- 积极的多模式治疗方法可能是必要的,以改善结果.
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