可穿戴的3D打印微针传感器用于皮肤内温度监测
Qikun Wei1, Daniel Rojas2, Qianyu Wang1
1Department of Chemistry, KTH Royal Institute of Technology, Teknikringen 30, Stockholm SE-114 28, Sweden.
ACS sensors
|April 15, 2025
概括
研究人员使用3D打印和导电聚合物开发了一种新的微针温度传感器 (T-MN). 该设备提供精确,连续的皮内温度监测,对于早期疾病诊断和患者护理至关重要.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 传感器技术 传感器技术
背景情况:
- 准确的皮肤内温度监测对于患者生理状况评估和早期疾病诊断至关重要.
- 目前用于连续皮内温度传感的方法在精度和可靠性方面面临挑战.
- 环境因素和皮肤分泌物可以干扰表面温度测量.
研究的目的:
- 开发一种高分辨率,机械稳固,生物相容的微针温度传感器 (T-MN),用于精确和连续的皮肤内温度监测.
- 为了利用3D打印和适应温度的导电聚合物 (PEDOT:PSS) 来制造T-MN.
- 评估T-MN用于皮内温度传感的分析性能和体内可靠性.
主要方法:
- 使用高分辨率3D打印制造空心微针.
- 用一个对温度有反应的导电聚合物 (聚3,4-乙烯二氧化) 填充微针:聚二硫酸盐,PEDOT:PSS).
- 在模仿的皮肤内条件下对传感器性能 (灵敏度,分辨率,稳定性) 的体外评估.
- 在安乐死的老鼠体内体温监测和与商业光学探针进行比较.
主要成果:
- 开发的T-MN表现出良好的灵敏度 (-0.74%°C-1),分辨率 (0.2°C),可重复性 (RSD=2%),可重复性 (RSD=2%),可逆性和中期稳定性.
- 在老鼠体内监测显示与商业光学温度探针有很好的一致性.
- 成功展示了精确和连续的皮肤内温度监测能力.
结论:
- 3D打印的微针温度传感器 (T-MN) 为持续的皮内温度监测提供了可靠的解决方案.
- 对于未来的患者监测和生物传感器中的温度补偿,T-MN技术具有显著的潜力.
- 这项工作突出了强大的微针的合理设计和用于先进传感应用的导电聚合物的实施.
相关概念视频
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Start by practicing proper hand hygiene to prevent the spread of microorganisms.
Step 2:
Take the thermometer out of the charging unit, switch it on, and wait for the ready sign.
Step 3:
Gently slide the probe cover until a click is heard. This simple action prevents cross-contamination and ensures the correct placement of the probe cover.
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Instruct the patient to open their mouth and place...
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Step 2: Prepare the patient by explaining the procedure to ensure understanding and cooperation. Ensure privacy, expose the axilla, and inform the patient that minimal movement is crucial for an accurate reading.
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01:14Assessing Body Temperature - Tympanic membrane
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Step 2: Turn on the thermometer and wait until the ready sign appears on the screen to ensure accurate measurement.
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Step 4: Instruct the patient to tilt their head to the side for comfort and check for cerumen...
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