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Updated: May 13, 2025

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转录因子占用限制了DNA甲基化,并决定了乳腺癌中ICAM1的表达

Mingcang Chen1,2, Ying Zhou3, Zhengwei Fu1

  • 1College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.

Acta biochimica et biophysica Sinica
|April 15, 2025
PubMed
概括

转录因子 (TF) 的结合减少了ICAM1促进体的DNA甲基化,增加了乳腺癌中ICAM1的表达. 这种表观遗传调节对于理解TF在癌症基因表达中的作用至关重要.

关键词:
通过DNA甲基化.乳腺癌 乳腺癌 乳腺癌竞争 竞争 竞争 竞争 竞争 竞争细胞间粘附分子 1 细胞间粘附分子 1转录因子结合的转录因子

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