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Updated: May 5, 2026

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干扰素调节因子8的表达和特征在布拉斯特性血细胞状树突细胞瘤和外节NK/T细胞淋巴瘤中,鼻类型

Yuejiao Lang1, Xiaoqin Dai1, Li Sun1

  • 1Department of Pathology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Histology and histopathology
|April 15, 2025
PubMed
概括

干扰素调节因子8 (IRF8) 在形血细胞状树突细胞瘤 (BPDCN) 和鼻类型的外节NK/T细胞淋巴瘤 (ENKTL) 中表达高. 这种诊断标志物对识别这些特定的血液淋巴瘤瘤有前途.

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The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
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