氨酸在预制CAD CAM骨块上的有效性用于脊柱增大:分裂口腔研究
Mohamed Hamdy Helal1, Mona S Sheta2, Aya Anwar Alsherif3
1Faculty of Dentistry, Oral Medicine, Periodontology, Oral Diagnosis, and Radiology Department, Tanta University, Tanta, Egypt.
Clinical implant dentistry and related research
|April 15, 2025
概括
氨酸 (HA) 与预制的CAD-CAM全基骨块相结合,显著增强了气膜脊增强,导致骨增强和骨质整合,使牙植入成功.
科学领域:
- 口腔和牙面部外科手术
- 生物材料科学 生物材料科学
- 恢复性牙科 恢复性牙科
背景情况:
- 膜脊增大对于恢复骨体积至关重要,但颗粒移植在体积控制方面存在挑战.
- 预制计算机辅助设计和计算机辅助制造 (CAD-CAM) 全基骨块提供了一个有前途的替代方案.
研究的目的:
- 为了评估预制CAD-CAM全基骨块与氨酸 (HA) 水合的疗效,与液对抗,用于膜脊增大.
- 为了比较两种水化方法之间的骨收益,组织学结果和植入物集成.
主要方法:
- 一个分裂口腔随机临床试验,涉及10名缩下患者.
- 使用CAD-CAM全源骨块进行增强,I组用HA和II组用盐水水化.
- 通过CBCT评估骨增加,核心活检用于组织学,并在6个月后植入植入物.
主要成果:
- 两组都取得了成功的骨增益,HA组的平均骨增益 (3.975毫米) 与盐酸组 (2.497毫米) 相比显著更大.
- 组织学分析显示,HA组的骨质整合和新骨形成优越.
- 随着HA水化,观察到VEGF,OPN和Cox 2的表达增加,以及更高的新骨表面积.
结论:
- 氨酸增强了预制CAD-CAM全基骨块的骨质性质.
- 这种方法确保了足够的移植集成,以成功插入牙植入物.
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