猫类慢性牙周炎:对相关因素的彻底系统审查
Mauricio Sánchez-Vallejo1, Paula Vélez-Velásquez2, Nathalia M Correa-Valencia1
1CENTAURO Research Group, School of Veterinary Medicine, Faculty of Agricultural Sciences, Universidad de Antioquia, Medellín, Colombia.
Journal of feline medicine and surgery
|April 15, 2025
概括
猫类慢性牙周炎 (FCGS) 与口腔微生物组的失衡以及像猫类卡利西病毒这样的传染剂有关. 免疫状况和环境因素也会导致猫的这种复杂的口腔炎症.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 免疫学 免疫学 免疫学
- 微生物学 微生物学
背景情况:
- 猫类慢性牙周炎 (FCGS) 是猫的严重,痛苦的口腔炎症状况.
- 目前尚不完全了解FCGS的确切原因,因此需要对促成因素进行全面审查.
- 现有研究强调了传染病原体,免疫反应和环境影响的潜在作用.
研究的目的:
- 系统地收集和分析有关猫类慢性牙周炎 (FCGS) 相关因素的现有证据.
- 综合有关宿主相关,环境和感染病原体的发现,这些病原体涉及到FCGS的病原体.
- 确定导致FCGS慢性炎症特征的关键因素.
主要方法:
- 在四个主要数据库 (OVID/MEDLINE,PubMed,SciELO,Redalyc) 进行电子文献搜索.
- 包括欧洲和兽医牙科论坛的文件,如果有.
- 应用了预先确定的包含和排除标准,专注于专家评审的期刊文章.
主要成果:
- 在1984年至2023年间发表的总共17篇文章符合纳入标准.
- 据报道,FCGS的全球发生率为10.9% (747/6881只猫).
- 探索的因素包括猫的内在特征,环境/管理方面,以及传染病原体 (例如,猫病毒[FCV],猫疹病毒1型[FHV-1],巴顿氏菌[Bartonella],Pasteurella multocida[Pasteurella multocida]),以及微生物组概况.
结论:
- 虽然确切的病因仍然难以捉摸,但口腔微生物组失生症和特定的传染病原体 (例如,Fusobacterium nucleatum,Porphyromonas,P multocida,FCV,FHV-1) 在FCGS病变发生过程中至关重要.
- 猫的免疫状况,包括与猫免疫缺陷病毒和猫白血病病毒 (FeLV) 的共感染,与增加的FCGS风险有关.
- 微生物失生症和免疫反应的改变是慢性炎症的关键驱动因素,非传染性因素也在疾病的复杂起源中发挥作用.
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