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Electroconvulsive Therapy01:30

Electroconvulsive Therapy

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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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Updated: May 13, 2025

Experimental Models to Study the Neuroprotection of Acidic Postconditioning Against Cerebral Ischemia
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远程缺血预调并不能缓解电后治疗认知功能障碍.

Ravitej Bhat1, Venkatapura J Ramesh2, Jagadisha Thirthalli3

  • 1From the Department of Anaesthesiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal.

The journal of ECT
|April 15, 2025
PubMed
概括
此摘要是机器生成的。

远程缺血预制 (RIPC) 在精神分裂症患者的电疗法 (ECT) 后没有减少认知功能障碍. 在ECT期间,RIPC被发现是安全的和可行的.

关键词:
在RIPC中,RIPC是RIPC.认知 认知 认知电疗法是一种电疗法.精神分裂症是一种精神分裂症.

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科学领域:

  • 神经科学是一个神经科学.
  • 精神病学是一个精神病学.
  • 临床试验 临床试验

背景情况:

  • 电疗法 (ECT) 用于严重的精神疾病.
  • 认知功能障碍是ECT常见的副作用之一.
  • 远程缺血预制 (RIPC) 正在研究神经保护作用.

研究的目的:

  • 评估RIPC在缓解精神分裂症患者在ECT后认知缺陷方面的有效性.
  • 评估RIPC在这个患者群体中的安全性和可行性.

主要方法:

  • 进行了一项随机对照试验.
  • 精神分裂症患者在六个ECT会议之前都接受了RIPC或假RIPC.
  • 认知和记忆功能使用标准化尺度 (HMSE,B4ECT ReCoDe,PGI,CGI-SI) 进行评估.

主要成果:

  • 在RIPC和假RIPC组之间的认知或记忆评估中没有发现显著差异.
  • 在两组中,社会人口统计和临床特征都相似.
  • 干预没有显示出对ECT后认知功能障碍的统计学意义上的影响.

结论:

  • 在精神分裂症患者中,RIPC没有有效地减少ECT后认知功能障碍.
  • 在接受ECT的患者中,RIPC被证明是安全的和可行的.
  • 干预并没有对主要的精神病状况产生不利影响.