三二甲氨酸通过降低亡和保存线粒体来保护心肌梗塞

Domenico Cerullo1, Polyxeni Mantzouratou1, Angelo M Lavecchia1

  • 1Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Department of Molecular Medicine, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Via Stezzano 87, 24126, Bergamo, Italy.

PubMed
概括

在心肌梗塞 (MI) 后的急性三甲氨酸 (T3) 治疗改善了心脏功能,并减少了心脏重塑. 这项研究表明,T3 保持了线粒体的完整性,并限制了细胞死亡,为心脏病发作恢复提供了一个有前途的治疗策略.

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