在读取结核病胸部放射图时,不同的Lunit INSIGHT CXR软件版本的比较
Andrew J Codlin1,2, Luan N Q Vo1,2, Thang P Dao1
1Friends for International TB Relief, Ha Noi, Viet Nam.
PLOS digital health
|April 15, 2025
概括
新的Lunit CAD软件用于结核病查显示性能有所改善,特别是在特定群体中. 重新校准切断值对于准确的胸部X射线解释与最新的计算机辅助检测工具至关重要.
科学领域:
- 医疗成像医学成像
- 结核病的诊断方法 结核病的诊断方法
- 软件性能评价 软件性能评价
背景情况:
- 定期更新计算机辅助检测 (CAD) 软件,用于肺结核 (TB) 查中的胸部X射线 (CXR) 解释,有望提高性能.
- 世界卫生组织推的INSIGHT CXR软件 (Lunit) 连续版本之间的性能差异缺乏独立评估.
研究的目的:
- 独立比较Lunit CAD软件版本3.1.0.0和3.9.0.1用于结核病查的性能.
- 用Xpert MTB/RIF Ultra作为参考标准来评估关键临床和人口学子组之间的绩效差异.
主要方法:
- 使用了来自越南结核病查计划的2,708名参与者的医学数字成像和通信 (DICOM) 测试库.
- 每个软件版本的接收器运行特征曲线 (AUC) 下的面积都被计算出来.
- 绩效按临床/人口统计变量分层,并在各种切断值进行比较.
主要成果:
- 新版本 (3.9.0.1) 与旧版本 (3.1.0.0) (0.76,p=0.029) 相比,显示出明显更高的AUC (0.78).
- 在有结核病史的个体,年长的个体和使用较新的软件的男性中,观察到性能改善.
- 当切断值重新校准时,版本之间没有观察到敏感性和特异性的显著差异.
结论:
- INSIGHT CXR v3.9.0.1 显示了与其前身相比更好的性能特征.
- 在实施新的CAD软件版本时,重新校准切断值至关重要,以保持TB查的CXR解释的准确性.
- 需要进一步的研究来确定这些软件性能差异的现实世界临床影响.
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