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Updated: May 13, 2025

Human Liver Spheroids from Peripheral Blood for Liver Disease Studies
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测量受孕前X受体调节的基因的表达和代谢活性,在人类初级肝细胞球体中

Lukáš Lochman1, Ellen Tanaka Kahiya2, Bechara Saade2

  • 1Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic.

PLoS computational biology
|April 15, 2025
PubMed
概括

这项研究使用数学建模来分析3D人类肝细胞中的孕前X受体 (PXR) 激活. 结果揭示了药物处理基因的长期PXR调节,为药物代谢和分泌提供了洞察力.

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