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[子中的急性呼吸道病毒感染]

D I Dogadov¹, K K Kyuregyan^2,3,4, A A Minosyan¹

¹Kurchatov Complex of Medical Primatology of NRC «Kurchatov Institute».

Voprosy virusologii

|April 15, 2025

概括

急性呼吸道病毒感染 (ARVI) 对灵长类健康构成重大风险,影响野生和被捕种群. 本综述分析了灵长类动物中的ARVI病原体及其在疫苗和药物开发的疾病建模中的使用.

科学领域:

兽医病毒学兽医病毒学
灵长类病理学
传染病流行病学传染病流行病学

背景情况:

急性呼吸道病毒感染 (ARVI) 是对灵长类健康的重大威胁,在囚禁和野生种群中引起显著的发病率和死亡率.
这些病毒也可以感染人类,突显了动物感染潜力和研究灵长类ARVI的重要性.
灵长类动物,包括人猿,对一系列ARVI敏感,在动物学和研究环境中有记录的爆发.

研究的目的:

审查和综合现有的关于ARVI病原体在不同灵长类动物种群中的流行和循环的文献.
分析灵长类动物在ARVI病原和传播中的作用,包括动物传染的影响.
评估灵长类动物模型在了解ARVI和开发对策方面的有用性.

主要方法:

关于野生和养灵长类动物中ARVI的已发表数据的综合文献搜索.
报告的ARVI病原体的分析,包括偏流感病毒,腺病毒,RSV,流感病毒,鼻病毒,冠状病毒,甲肺病毒和口腔病毒.
审查涉及对非人类灵长类动物ARVI实验建模的研究.

主要成果:

艾滋病病毒病原体在各种灵长类动物中广泛存在,影响了自由活动和被囚禁的个体.
在动物园设施中记录的疫情强调了灵长类动物对这些病原体的易感性.
灵长类动物模型为ARVI生物学,病变发生提供了关键的见解,并作为治疗和疫苗测试的平台.

结论:

了解灵长类动物中的ARVI动态对于动物保护,动物福利和公共卫生至关重要,因为有动物传染风险.
灵长类动物作为研究ARVI的宝贵模型,有助于开发有效的干预措施.
对灵长类动物的ARVI的持续研究对于管理疾病爆发和推进生物医学研究至关重要.

关键词:

这里是ARVI.这些子是子.审查审查审查审查审查审查

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