工业空气污染和新生儿听力查失败
Yanhong Huang1, Yan Lin2, Roberta P Lavin3
1Department of Geography & Environmental Studies and UNM Center for the Advancement of Spatial Informatics Research and Education (ASPIRE), University of New Mexico, Albuquerque, NM, 87131, USA.
Journal of hazardous materials
|April 15, 2025
概括
母亲接触空气污染中的某些金属与新生儿听力查失败有关. 减少接触这些空气中的金属可能会改善婴儿的听力健康.
科学领域:
- 环境健康 环境健康
- 儿科 儿科 儿科
- 毒理学 毒理学 毒理学
背景情况:
- 新生儿听力损失影响语言和认知发育.
- 空气污染中的金属与不利的出生结果有关.
- 暴露于金属和婴儿听力损失之间的潜在联系尚未得到充分探索.
研究的目的:
- 调查母亲暴露于PM2.5结合金属和新生儿听力查 (NHS) 失败之间的关联.
- 确定有助于增加新生儿听力损失风险的特定金属.
主要方法:
- 在新墨西哥州 (2008-2017年) 进行了141,406例新生儿的回顾性队列研究.
- 使用风险选环境指标 (RSEI) 模型对PM2.5结合金属进行暴露评估.
- 空间日志双项回归分析,以计算NHS失败的调整相对风险 (aRR).
主要成果:
- 母亲暴露于PM2.5中的,,,,,,,,,和,与NHS失败 (aRRs1.07-2.18) 有积极关联.
- 观察到一种剂量反应趋势,这些金属的暴露水平越来越高.
- 即使经过对混因素进行调整后,也发现了显著的关联.
结论:
- 孕妇在怀孕期间暴露于特定的PM2.5结合金属是新生儿听力损失的危险因素.
- 空气污染,特别是含有金属的颗粒物,是婴儿听力健康的可修改风险因素.
- 调查结果强调了需要采取干预措施来减少孕妇环境金属暴露的必要性.
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