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Updated: May 13, 2025

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LOXHD1是一种Ewing肉瘤的融合调节抗原

Tatiana Blanchard1, Pouya Faridi2,3,4,5, Chong Xu6

  • 1Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Scientific reports
|April 15, 2025
PubMed
概括

脂氧酶同质域1 (LOXHD1) 是Ewing肉瘤 (EwS) 免疫治疗的新目标. 在临床前模型中,LOXHD1特异性T细胞根除了EWS瘤,突出了其作为瘤相关抗原的潜力.

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