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Updated: Jun 24, 2026

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay
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CD95/Fas静脉测量在未来的精密医学中的作用

Mauricio Sica1, Murielle Roussel2,3, Patrick Legembre4

  • 1CONICET, Instituto Balseiro (UNCuyo), Departamento de Física Médica (GAANS-CNEA), Bariloche Atomic Center, Av. Bustillo 9500, Bariloche, Río Negro, Argentina. mp.sica@gmail.com.

Cell death and differentiation
|April 15, 2025
PubMed
概括

在细胞膜上,CD95 (Fas) 受体是前相关的. 了解它的结构是开发用于免疫疾病的药物的关键,因为突变会导致自身免疫和炎症.

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Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...