在健康成年人中确定常见肝功能测试的参考间隔
Abdul Baset Abbas1, Ashraf Yahya2, Zakaria Aloqab2
1Medical Laboratories Department, Faculty of Medicine and Health Sciences, Ibb University, Ibb City, 70270, Yemen. abduabbas@ibbuniv.edu.ye.
Scientific reports
|April 15, 2025
概括
这项研究确定了也门伊布市成年人肝功能测试 (LFT) 的局部参考间隔 (RI). 结果显示,在LFT中存在显著的基于性别的差异,突出了对特定区域的RI的需求.
科学领域:
- 临床生物化学 临床生物化学
- 实验室医学 实验室医学
- 公共卫生 公共卫生
背景情况:
- 在医疗保健中,参考间隔对于解释实验室结果至关重要.
- 已建立的RI受到各种人口和环境因素的影响.
- 现有的RI可能不准确地反映当地人口,需要进行特定区域的研究.
研究的目的:
- 在健康成年人中确定常见肝功能测试 (LFT) 的参考间隔.
- 调查研究人口中LFT的潜在基于性别的差异.
- 为也门Ibb市建立当地相关的RI.
主要方法:
- 一项涉及390名18至70岁的健康成年人的横截面研究,在也门伊布市.
- 数据收集包括问卷和血清肝功能测试 (DBIL,TBIL,ALB,TP,ALP,AST,ALT) 的分析.
- 使用Mindray BS-240分析仪进行分析,使用GraphPad Prism 8.0.1.1.处理数据.
主要成果:
- 观察到基于性别的显著差异,男性的DBIL,TBIL,ALB,ALP和ALT的RI较高.
- TP和AST在男性中显示出更高的RI,尽管这些差异在统计学上并不显著.
- 大多数确定的RI不同于其他国家报告的RI,这表明当地存在差异.
结论:
- 这项研究提供了Ibb市成年人常见LFT的当地相关参考区间组.
- 这些发现强调了使用地理特定RI来准确的临床解释的重要性.
- 这些本地产生的RI可以帮助诊断,预后和监测也门人口的肝脏健康.
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